2005-2006 University of Guelph Undergraduate Calendar

XII. Course Descriptions

Biochemistry

Department of Molecular and Cellular Biology.

BIOC*2580 Introductory Biochemistry S,F,W (3-3) [0.50]
The evolution, chemical structure, and biological roles of the major molecular components of the cell: proteins, nucleic acids, lipids, and carbohydrates, enzymology, intermediary metabolism, with emphasis on catabolic processes.
Prerequisite(s): CHEM*1050 or CHEM*2300
BIOC*3560 Structure and Function in Biochemistry F,W (3-0) [0.50]
This course develops the understanding of biochemical processes, by examining the enzymatic molecular mechanisms underlying specific cellular and physiological systems. Examples may include oxygen binding/transport and the evolution of globin genes/proteins; regulation of carbohydrate and lipid metabolism; proteins that change shape, including enzymes, membrane proteins, and prion proteins, blood clotting; neurotransmission.
Prerequisite(s): BIOC*2580
BIOC*3570 Analytical Biochemistry S,F (3-3) [0.50]
The tools and techniques by which biological molecules are isolated, separated, identified, and analyzed. Detailed discussion of experimental methods for macromolecule purification characterization.
Prerequisite(s): (CHEM*2400 or CHEM*2480), BIOC*2580
Restriction(s): MICR*3110
BIOC*4520 Metabolic Processes F (3-0) [0.50]
An in-depth study of the role of bioenergetics, regulation, and chemical mechanisms in carbohydrate, lipid, and nitrogen metabolism.
Prerequisite(s): BIOC*3560 or BIOC*3570
BIOC*4540 Enzymology W (2-4) [0.50]
A laboratory-intensive course. Enzyme active sites and the mechisms of enzyme action; enzyme kinetics and regulation; recombinant proteins and site-directed mutagenesis as tools for understanding enzymes.
Prerequisite(s): BIOC*3560 (may be taken concurrently), BIOC*3570
BIOC*4550 Biochemistry and Structure of Macromolecules F (3-0) [0.50]
Structure, function, and physical conformation of proteins and nucleic acids, biophysical and computational techniques for the study of biological macromolecules.
Prerequisite(s): (BIOC*3570 and 1 of CHEM*2820, CHEM*2880) or (BIOC*3560*, PHYS*3240)
BIOC*4570 Applied Biochemistry F (3-0) [0.50]
Biochemical engineering of the pathways for production of amino acids, antibiotics, proteins, enzymes, and antibodies for applications in industry, medicine and scientific research.
Prerequisite(s): BIOC*3560 or BIOC*3570
BIOC*4580 Membrane Biochemistry W (3-0) [0.50]
An examination at the molecular level of structure and functions of cell membranes, cell surfaces and associated structures. Topics may include: membrane lipids; membrane protein structure; membrane transporters; ATP production; cytoskeleton; cell surface carbohydrates; membrane biogenesis; signal transduction.
Prerequisite(s): BIOC*3560 or BIOC*3570