XII. Course Descriptions
Molecular Biology and Genetics
Department of Animal Biosciences
Department of Molecular and Cellular Biology
Department of Plant Agriculture
Department of Integrative Biology
| MBG*1000 Genetics and Society W (3-1) [0.50] |
| This course covers the basic principles of genetics at work in human society. The roles of genes and inheritance in the biology
of humans and the organisms with which we interact. Introduction to some of the social and ethical consequences of genetic
knowledge and practice. This is a science course designed primarily for students in the Arts or Social and Applied Human Sciences.
|
| Restriction(s): |
Students in the BAS, BSC and BSC(ENV) program cannot take this course for credit. |
| Department(s): |
Department of Molecular and Cellular
Biology
|
| MBG*2040 Foundations in Molecular Biology and Genetics F,W (4-0) [0.50] |
| This course will develop an understanding of the fundamental concepts in genetics, including patterns of inheritance, allelic
variation, gene interaction, linkage, gene mapping and changes in chromosome structure and number. This will be followed by
in-depth discussions on gene structure, replication, transcription, translation, recombination, mutation and DNA repair, and
an introduction to gene regulation.
|
| Prerequisite(s): |
4.00 credits including BIOL*1090 |
| Department(s): |
Department of Molecular and Cellular
Biology
|
| MBG*2400 Fundamentals of Plant and Animal Genetics F (3-2) [0.50] |
| Fundamental aspects of plant and animal genetics are covered in this course including the chromosomal basis of inheritance,
natural and artificial selection, domestication, epigenetics and quantitative traits. Population dynamics and the effect of
selection on allele frequencies will be introduced with examples from agricultural crop and animal species and companion animal
species. Genomics will be introduced with an emphasis on the development and use of molecular genetic markers in marker assisted
selection.
|
| Prerequisite(s): |
(BIOL*1050 or BIOL*1070), BIOL*1090 |
| Department(s): |
Department of Animal Biosciences |
| MBG*3040 Molecular Biology of the Gene F (3-0) [0.50] |
| In this course, the structure, expression, control and modification of eukaryotic genes will be discussed with an emphasis
on the underlying mechanisms and structure/function relationships. Many topics covered in introductory courses are included
but discussed at a more advanced level. Students will have the opportunity to learn current genetic concepts and principles
through lectures, as well as the application of this knowledge in the real world through primary literature reading and group
research projects.
|
| Prerequisite(s): |
MCB*2050 |
| Restriction(s): |
MBG*4080 |
| Department(s): |
Department of Molecular and Cellular
Biology
|
| MBG*3050 Human Genetics W (3-3) [0.50] |
| This course is designed to introduce the student to the study of biological inheritance in humans. The course includes discussion
of the genetic basis of human individual differences, gene frequencies in human populations, human behavioral genetics, human
cytogenetics, biochemical genetics and developmental genetics, medical genetics and other aspects of human heredity.
|
| Prerequisite(s): |
MCB*2050 |
| Department(s): |
Department of Molecular and Cellular
Biology
|
| MBG*3060 Quantitative Genetics W (3-0) [0.50] |
| This course examines the nature of Mendelian inheritance when extended to quantitative traits that are jointly influenced
by the environment and the simultaneous segregation of many genes. Prediction of response to natural and artificial selection
in populations will also be studied.
|
| Offering(s): |
Also offered through Distance Education format. |
| Prerequisite(s): |
MBG*2400, 0.50 credits in statistics
|
| Department(s): |
Department of Animal Biosciences |
| MBG*3080 Bacterial Genetics F (3-0) [0.50] |
| This course focuses on the genetics of prokaryotic microorganisms and their viruses. Some major topics covered are: regulation
of gene expression, analysis of bacterial and phage genomes, plasmids, transposable elements, and mutation studies.
|
| Prerequisite(s): |
MBG*2040, MICR*2420 |
| Department(s): |
Department of Molecular and Cellular
Biology
|
| MBG*3100 Plant Genetics W (3-2) [0.50] |
| This course examines reproduction in plants, genome organization, organelle and polyploid genetics, and analyses of mutations,
genetic variation and linkage with classical and modern approaches.
|
| Prerequisite(s): |
(MBG*2040 or MBG*2400 ), STAT*2040 |
| Department(s): |
Department of Plant Agriculture |
| MBG*3350 Laboratory Methods in Molecular Biology I F,W (1.5-8) [0.75] |
| This course involves laboratory based instruction in the basic methodologies of Molecular Biology. Students will have the
opportunity to develop technical skills and practical knowledge sufficient to perform basic procedures independently, and
to diagnose and analyze experimental results obtained with these techniques.
|
| Prerequisite(s): |
BIOC*2580, MCB*2050 |
| Restriction(s): |
Registration in BSC.BIOC (major or minor), BIOC:C , BTOX, BTOX:C, BPCH, BPCH:C, MICR(major or minor), MICR:C , MBG (major
or minor), PBTC, PLSC (major or minor), TOX, TOX:C
|
| Department(s): |
Department of Molecular and Cellular
Biology
|
| MBG*3360 Laboratory Methods in Molecular Biology II W (0-8) [0.75] |
| This is a laboratory based course which builds on the techniques introduced in MBG*3350. Students will have the opportunity to develop technical skills and practical knowledge sufficient to perform advanced procedures
independently, and to diagnose and analyze experimental results obtained with these techniques.
|
| Prerequisite(s): |
70% in MCB*2050 and 75% in MBG*3350 |
| Department(s): |
Department of Molecular and Cellular
Biology
|
| MBG*3660 Genomics W (3-0) [0.50] |
| This course examines the genomes of eukaryotes and prokaryotes including how genomes are mapped and sequenced, the function
of the genome and ethical issues arising from genomic information. How genomic data is used for understanding and treating
human disease and for the study of evolution will also be discussed.
|
| Prerequisite(s): |
MCB*2050 |
| Department(s): |
Department of Molecular and Cellular
Biology
|
| MBG*4020 Genetics of Companion Animals F (3-0) [0.50] |
| This course explores theoretical and applied aspects of breeding programs for performance, pleasure and hobby animal populations
to enhance genetic selection and population viability. Case studies are used to explore the theory and practice of designing
practical and sustainable breeding programs that integrate molecular genetics, animal breeding and statistical genomics for
a variety of single and multiple birth species.
|
| Prerequisite(s): |
MBG*3060 |
| Equate(s): |
ANSC*4020 |
| Department(s): |
Department of Animal Biosciences |
| MBG*4030 Animal Breeding Methods and Applications W (3-2) [0.50] |
| Theoretical and scientific aspects of practical animal breeding programs which lead to genetic improvement of efficiency and
profitability of animal production will be presented along with applications to livestock and poultry species. This course
integrates quantitative genetics with concepts of statistics, economics, biology and biotechnology and expands into development
of practical breeding plans.
|
| Prerequisite(s): |
MBG*3060 |
| Department(s): |
Department of Animal Biosciences |
| MBG*4110 Epigenetics F (3-0) [0.50] |
| This course presents classical non-Mendelian phenomena, including analysis of chromosome breakage, transposition, imprinting
and paramutation. Modern advances in gene regulation via epigenetic phenomena will be a central theme, focusing on chromatic
remodeling, gene silencing and RNA interference as they pertain to organism development, with an emphasis on plants.
|
| Prerequisite(s): |
MCB*2050 or MBG*3040 |
| Department(s): |
Department of Molecular and Cellular
Biology
|
| MBG*4160 Plant Breeding F (3-2) [0.50] |
| This course examines the application of genetic principles to plant improvement. Topics include breeding objectives, mating
systems, selection, testing and germplasm maintenance of horticultural and crop plants.
|
| Prerequisite(s): |
(MBG*2040 or MBG*2400), STAT*2040 |
| Department(s): |
Department of Plant Agriculture |
| MBG*4240 Applied Molecular Genetics in Medicine and Biotechnology W (3-0) [0.50] |
| This course will examine advanced techniques and methods used in molecular biology, medicine and biotechnology such as genome,
transcriptome and proteome analysis, contemporary genetic screens, genetic engineering, transgenic organisms and gene therapy.
The course will highlight the most recent developments and applications of such techniques.
|
| Prerequisite(s): |
MCB*2050 or MBG*3040 |
| Department(s): |
Department of Molecular and Cellular
Biology
|
| MBG*4270 DNA Replication, Recombination and Repair W (3-0) [0.50] |
| This course will examine the DNA transactions that determine the structure and function of the genome, with an emphasis on
natural and synthetic mutagens and their mode of action, replication and recombination of genetic material, recognition and
repair of DNA damage, and inherited and somatic genetic diseases arising from abnormal DNA metabolism.
|
| Prerequisite(s): |
MCB*2050 |
| Department(s): |
Department of Molecular and Cellular
Biology
|
| MBG*4300 Plant Molecular Genetics F (3-0) [0.50] |
| This course studies the molecular genetics of plants. The topics include: plant genome diversity and synteny; Arabidopsis
thaliana genome, hormonal, environmental and developmental regulation of gene expression; chloroplast and mitochondrial genomes;
and gene expression and silencing in transgenics. The course will be delivered using a lecture and paper discussion format.
Students will learn and use a variety of computer techniques to search and analyze plant genome databases.
|
| Offering(s): |
Offered in odd-numbered years. |
| Prerequisite(s): |
MBG*2040 or MBG*2400 |
| Department(s): |
Department of Plant Agriculture |
